Physica

07 MRI

T2* from T2 and field inhomogeneity

1/T2* = 1/T2 + γ ΔB. Extra dephasing from local field offsets.

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Simulation

T2* from T2 and field inhomogeneity — Change the numbers; the scene follows.

Where it works

MRI scanner

MRI scanner

Main magnet

In the main magnet — B₀ sets Larmor frequency and the local field that drives T2*.

Open this machine

Formula

1/T2=1/T2+γΔB1/T_2^*=1/T_2+\gamma\Delta B

Variables

Results

  • T₂*

    T2 star

    6.8372ms

  • R₂′

    Inhomogeneous decay rate

    133.76s⁻¹

Explanation

1/T2=1/T2+γΔB1/T_2^*=1/T_2+\gamma\Delta B

What it means

T2* is shorter than T2 because of extra dephasing from field offsets: 1/T2* = 1/T2 + γ ΔB. GRE, SWI and BOLD contrast live on T2*. A 0.5 µT offset already pulls T2* down hard. This is a working relation in MRI physics.

Where it is used

Clinically it sits on the MRI scanner — Main magnet. In the main magnet — B₀ sets Larmor frequency and the local field that drives T2*. MRI physics lives in the magnet, the gradient, and the voxel: Larmor, Ernst, diffusion, and SAR. These relations decide whether a sequence is possible, safe, and worth the time.

MRI scanner · Open this machine

How to use it

Enter tissue T2 (ms) and a local ΔB (µT). Near air/tissue (sinuses) ΔB is large and GRE signal vanishes — that is the susceptibility artefact. Change one input and watch the curve and the simulation follow.

Symbols

  • T₂Transverse relaxation80 ms
  • ΔBField offset0.5 µT

Worked example

A typical case from the default values: T₂ = 80 ms (Transverse relaxation); ΔB = 0.5 µT (Field offset). Substituting into the relation gives T₂* = 6.8372 ms; R₂′ = 133.76 s⁻¹. These are teaching numbers — align them with your machine.

Typical values give

  • T₂* = 6.8372ms
  • R₂′ = 133.76s⁻¹

Where it comes from

The displayed formula is the working relation. 1/T2* = 1/T2 + γ ΔB. Extra dephasing from local field offsets. Usual reference: McRobbie. Derive it in the specialty lesson, then return here to pin the numbers.

Reference: McRobbie

Assumptions & limits

Static Lorentzian/Gaussian offset, not diffusion through gradients (that is T2′ vs ADC). SE refocuses this term; GRE does not.

Pitfalls

γ for ¹H is not γ for ¹³C. Ernst angle needs the true T1 at that field, not a 1.5 T table used at 3 T. SAR scales with B₀² and flip² — a 3 T copy of a 1.5 T protocol is not automatically legal. Static Lorentzian/Gaussian offset, not diffusion through gradients (that is T2′ vs ADC). SE refocuses this term; GRE does not.

Keep this

γ here is in rad s⁻¹ T⁻¹. ΔB in µT. T2 and T2* in ms.

In this specialty

MRI physics