Physica

07 MRI

Inversion-recovery signal

M_z(TI) = M₀ (1 − 2 e^{−TI/T1} + e^{−TR/T1}). Null when TI = T1 ln 2 (long TR).

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Simulation

Inversion-recovery signal — Change the numbers; the scene follows.

Where it works

MRI scanner

MRI scanner

RF coil

At the RF coil — flip angle, SAR, SNR, receive bandwidth, and the pulse sequence.

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Formula

Mz=M0(12eTI/T1+eTR/T1)M_z=M_0\left(1-2e^{-TI/T_1}+e^{-TR/T_1}\right)

Variables

Results

  • M_z/M_0

    Longitudinal magnetisation

    -0.0542

  • TI_null

    Null TI (long TR)

    173.2868ms

Curve

Explanation

Mz=M0(12eTI/T1+eTR/T1)M_z=M_0\left(1-2e^{-TI/T_1}+e^{-TR/T_1}\right)

What it means

A 180° pulse inverts M_z; it recovers through zero at TI ≈ T1 ln 2 (0.69 T1) if TR ≫ T1. STIR nulls fat (T1 ~ 250 ms at 1.5 T → TI ~ 150–170 ms). FLAIR nulls CSF (T1 ~ 4000 ms → TI ~ 2000–2500 ms). Magnitude images fold the negative lobe, so the null is a dark band rather than a sign change (unless phase-sensitive IR is used). This is a working relation in MRI physics.

Where it is used

Clinically it sits on the MRI scanner — RF coil. At the RF coil — flip angle, SAR, SNR, receive bandwidth, and the pulse sequence. MRI physics lives in the magnet, the gradient, and the voxel: Larmor, Ernst, diffusion, and SAR. These relations decide whether a sequence is possible, safe, and worth the time.

MRI scanner · Open this machine

How to use it

Enter T1, TI, TR (ms). Read Mz/M0 and the null TI for this T1 (long-TR formula T1 ln 2, plus the finite-TR correction). Fat at 1.5 T: T1=250, TI=160, TR=2000. Change one input and watch the curve and the simulation follow.

Symbols

  • T1Longitudinal relaxation250 ms
  • TIInversion time160 ms
  • TRRepetition time2,000 ms

Worked example

A typical case from the default values: T1 = 250 ms (Longitudinal relaxation); TI = 160 ms (Inversion time); TR = 2,000 ms (Repetition time). Substituting into the relation gives M_z/M_0 = -0.0542; TI_null = 173.2868 ms. These are teaching numbers — align them with your machine.

Typical values give

  • M_z/M_0 = -0.0542
  • TI_null = 173.2868ms

Where it comes from

The displayed formula is the working relation. M_z(TI) = M₀ (1 − 2 e^{−TI/T1} + e^{−TR/T1}). Null when TI = T1 ln 2 (long TR). Usual reference: McRobbie / Bernstein. Derive it in the specialty lesson, then return here to pin the numbers.

Reference: McRobbie / Bernstein

Assumptions & limits

Perfect 180°, no residual xy, spoiled. Magnitude vs signed is not selected — the calculator reports signed Mz. STIR also has a J-coupling / T2 effect on fat that this 1-D model ignores.

Pitfalls

γ for ¹H is not γ for ¹³C. Ernst angle needs the true T1 at that field, not a 1.5 T table used at 3 T. SAR scales with B₀² and flip² — a 3 T copy of a 1.5 T protocol is not automatically legal. Perfect 180°, no residual xy, spoiled. Magnitude vs signed is not selected — the calculator reports signed Mz. STIR also has a J-coupling / T2 effect on fat that this 1-D model ignores.

Keep this

Name the nucleus and the field before you quote a Larmor frequency. Perfect 180°, no residual xy, spoiled. Magnitude vs signed is not selected — the calculator reports signed Mz. STIR also has a J-coupling / T2 effect on fat that this 1-D model ignores.

In this specialty

MRI physics