Physica

07 MRI

Diffusion b-value

b = (γ G δ)² (Δ − δ/3) for a pair of rectangular pulses (Stejskal–Tanner).

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Simulation

Diffusion b-value — Change the numbers; the scene follows.

Where it works

MRI scanner

MRI scanner

Gradient coils

In the gradient coils — slice thickness, FOV, diffusion encoding, voxel size.

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Formula

b=(γGδ)2(Δδ/3)b=(\gamma G\delta)^2(\Delta-\delta/3)

Variables

Results

  • b

    b-value

    858.8174s/mm²

  • Δ−δ/3

    Effective diffusion time

    33.3333ms

Explanation

b=(γGδ)2(Δδ/3)b=(\gamma G\delta)^2(\Delta-\delta/3)

What it means

The b-value is the diffusion-weighting dose: how hard the sequence punishes moving spins. Two matched gradient lobes around the 180° (spin-echo) or of opposite sign (STEAM) give b ∝ G² δ² (Δ − δ/3). Clinical DWI uses b = 0 and b = 800–1000 s/mm²; oncology and body DWI go to 1500–2000. ADC maps are a fit of ln S versus b. This is a working relation in MRI physics.

Where it is used

Clinically it sits on the MRI scanner — Gradient coils. In the gradient coils — slice thickness, FOV, diffusion encoding, voxel size. MRI physics lives in the magnet, the gradient, and the voxel: Larmor, Ernst, diffusion, and SAR. These relations decide whether a sequence is possible, safe, and worth the time.

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How to use it

Enter G (mT/m), lobe duration δ (ms) and spacing Δ (ms). γ for ¹H is built in (42.58 MHz/T = 2.675×10⁸ rad/s/T). 30 mT/m, δ = 20 ms, Δ = 40 ms → b ≈ 850 s/mm². Change one input and watch the curve and the simulation follow.

Symbols

  • GGradient amplitude30 mT/m
  • δLobe duration20 ms
  • ΔLobe spacing40 ms

Worked example

A typical case from the default values: G = 30 mT/m (Gradient amplitude); δ = 20 ms (Lobe duration); Δ = 40 ms (Lobe spacing). Substituting into the relation gives b = 858.8174 s/mm²; Δ−δ/3 = 33.3333 ms. These are teaching numbers — align them with your machine.

Typical values give

  • b = 858.8174s/mm²
  • Δ−δ/3 = 33.3333ms

Where it comes from

The displayed formula is the working relation. b = (γ G δ)² (Δ − δ/3) for a pair of rectangular pulses (Stejskal–Tanner). Usual reference: Stejskal & Tanner 1965 / McRobbie. Derive it in the specialty lesson, then return here to pin the numbers.

Reference: Stejskal & Tanner 1965 / McRobbie

Assumptions & limits

Rectangular lobes, no ramp time, no imaging gradients. Real EPI-DWI b-matrices include the readout train and are 3×3 tensors (anisotropy). Cross-terms appear when you combine axes.

Pitfalls

γ for ¹H is not γ for ¹³C. Ernst angle needs the true T1 at that field, not a 1.5 T table used at 3 T. SAR scales with B₀² and flip² — a 3 T copy of a 1.5 T protocol is not automatically legal. Rectangular lobes, no ramp time, no imaging gradients. Real EPI-DWI b-matrices include the readout train and are 3×3 tensors (anisotropy). Cross-terms appear when you combine axes.

Keep this

Name the nucleus and the field before you quote a Larmor frequency. Rectangular lobes, no ramp time, no imaging gradients. Real EPI-DWI b-matrices include the readout train and are 3×3 tensors (anisotropy). Cross-terms appear when you combine axes.

In this specialty

MRI physics