Radiobiology

Topics

• 4.1History of radiation injuries in humans
• 4.2Radiation interactions in cells and tissues
• 4.3Radiation injury to DNA
• 4.4Repair of DNA damage
• 4.5Indirect effects of radiation
• 4.6Chromosomal damage and repair
• 4.7Target theory and cell survival curves
• 4.8Free radical formation
• 4.9Apoptosis and reproductive cell death
• 4.10Cell kinetics
  • 4.10.1Cell recovery processes
  • 4.10.2Cell cycle sensitivity
• 4.11Radioprotectors and radiosensitizers
• 4.12RBE, OER, LET
• 4.13Tissue injuries
  • 4.13.1Acute effects of radiation
  • 4.13.2Delayed effects of radiation
  • 4.13.3Radiation carcinogenesis
  • 4.13.4Radiation mutagenesis
  • 4.13.5Radiation teratogenesis
  • 4.13.6Other embryo and fetal effects
• 4.14Risk estimates of radiation
• 4.15History of the linear no-threshold theory
• 4.16Predictions of cancers in populations
• 4.17Radiation epidemiology
• 4.18Evidence of cancers in populations
• 4.19Concept of radiation hormesis
• 4.20Tumor radiobiology
• 4.21Time, dose, fractionation
• 4.22Molecular mechanisms
• 4.23Drug and radiation interactions